Department of Human Genetics , Punjabi University, Patiala
 Department History | Thrust Areas |Courses Offered & Admission Criteria | Teaching Faculty | Technical & Non-Teaching Staff  | Research Staff | Research Projects Undertaken | List of Ongoing projects  |Infrastructure Facilities | significant Achievements | Collaborations | Contact Us

Department History

The Department of Human Genetics earlier known as the Department of Human Biology was established in 1970 under the leadership of Professor L.S. Sidhu and Professor  I.J.S. Bansal. A UGC-funded research centre in Physical Education and Sports was set up in 1973 which became an independent Department of Sports Sciences in 1989. A ‘Human Antigen Research Programme’ was initiated in 1975 under the guidance of Prof. P.K. Shrivastava and an animal house was built in a separate building. In this programme, studies were conducted on different populations and two novel antigens, DD from dandruff and LH from serum were identified. Major and minor research projects were granted to the department by various agencies such as UGC, ICMR, CSIR, DOE, DST etc. The Department has a rich history of providing supervision for M.D., M.Sc. and a comprehensive doctoral research programme in the fields of immunogenetics, human population genetics, biochemical genetics, cytogenetics, molecular genetics and human growth and development. Till date, 110 Ph.D. degrees have been awarded.

The Department was identified for financial support by DST under FIST programme in 2009 and by UGC under special assistance programme (SAP) in 2011. With this financial support, the department has further strengthened teaching and research by setting up two centralized research laboratories which house major equipments including Fluorescent microscope, PCR machines, Gel documentation system, Biochemistry analyzer,  ELISA plate reader, Deep freezer etc. and a computer lab with internet facility.


Thrust Areas

Currently, the faculty members and research students of the department are working under the following thrust areas:
1. Genetic investigation of complex disorders
2. Genotoxicity testing of occupationally exposed individuals
3. Molecular characterization of Human Cancers
4. Human growth and development
5. Nutrigenomics of complex diseases

Courses Offered and Admission Criteria

S.No.

Course

Duration

Seats

Eligibility

Admission criteria

1. 

M.Sc.(2 years): Human Genetics 

 2 years

30   

B.Sc. with any of the following subjects :-

Human Genetics, Biochemistry, Bioinformatics, Botany, Zoology, Chemistry, Anthropology, Anatomy, Physiology, Microbiology

Merit in the Qualifying Examination 

2. 

Doctoral Programme    

 

 

 

 





Faculty

Name Telephone Number E-mail
 
Professor & Head
Dr. Satbir Kaur 0175-2217170      
9815350801
satbir@pbi.ac.in, satbirkia@yahoo.co.in
 Assistant Professor
Dr. Rupinder Kaur Bansal
     
0175-3406598
9872886304
  bansaljolly1@rediffmail.com
Dr. Rajinder Kaur 9876395699   rtrasool@yahoo.co.in
Dr. Ginjinder Kaur 9216142474 ginjinder_lamba@rediffmail.com
Dr. Puneetpal Singh          9646448947 singh.puneet@rediffmail.com Puneetpalsingh@pbi.ac.in
 Professor (Re-employed)
Dr. S.M.S. Chahal 0175-2286304
9876096304
 smschahal@rediffmail.com
Dr. Promila Mehta 0175-2309786
9478258900
Mehta.Promila@rediffmail.com


Technical & Non-Teaching Staff

Name Telephone Number E-mail

 Laboratory Superintendent

Dr. Rajinder Kumar

 9815321565

  

  Technical Assistant

 Non Teaching Staff
Harpreet Singh
(Office In charge)
 9876220636   harpreetS_sms@rediffmail.com
Bachan Kumar
(Daftri)
 9815784007   

 Junior Technical Assistant

Gurinder Singh

 9501277009

  

Sahib Singh

9779173977

 Lab/ Museum Attendant

Dalip Kumar

 9815481639

  

Sahil Arya

9988676782

Balinder Kaur

9646132163





Research Staff

Name  Qualification Designation Specialization Title of the Project Funding Agency
1. Shobha R. Dhiman

2. Monica Singh

M.Sc. Ph.D

 

M.Sc.,Ph.D                    

UGC Research Scientist "B"
                              

Research Scientist

Human Genetics

Human Genetics

Immunoglobulin all types in health and disease  
                                                           
Essential hypertension and its genetic link with bone mineral density by investigating some selected candidate genes in post menopausal female of Northwest India
UGC, New Delhi

DST, New Delhi. 



RESEARCH PROJECTS UNDERTAKEN

Major Research Projects


A number of Major and Minor research projects sponsored by various funding agencies such as the UGC, CSIR, ICMR, DOE etc. have been awarded and executed successfully by the faculty members from time to time.

Following is the list of the Major Research Projects:

Year

Project title

Agency

Investigator(s)

Amount

  (Rs.)

1973

Research Centre in Physical Education and Sports

UGC

Sh.S.K. Mahindroo,          Dr. L.S.Sidhu

1975

Human Antigens Research Programme

UGC

Dr.P.K.Shrivastava,              

Dr. I.J.S.  Bansal,       

Dr. Lakhbir Singh

4 lac

1982

Cytogenetic Study of Childlessness

UGC

Dr. I.J.S. Bansal,        

Dr. Lakhbir Singh

4 lac

1987

Impact of Modernization Activities and Changing Environment on Demogenetic Composition of Human Populations of Garhwal, U.P. Himalayas

DOE

Dr. I.J.S. Bansal,        

Dr. S.M.S. Chahal

5 lac

1988

Genetic Differentiation in Punjab Populations

UGC

Dr. S.M.S. Chahal

2.5 lac

1988

Dandruff Reactivity in Various Ecozones

CSIR

Dr. P.K. Shrivastava,         Dr. Harsurinder Kaur

2.5 lac

1989

Secular Trend and Ageing in Two Endogamous Groups Living Under Varied Ecological Conditions in India

UGC

Dr. L.S. Sidhu,        

Dr. Pushpa Singal

2 Lac

1990

Blood Group Antigens, Plasma Proteins and Red Cell Isoenzyme Polymorphisms in Health and Disease

UGC

Dr. D.P. Bhatnagar

2 lac

1992

Genetic Polymorphism of Lipoprotein Among Some Ethnic Groups of Punjab

UGC

Dr. I.J.S. Bansal,     

 Dr. Parveen Pal Balgir

3 lac

1992

Cis-AB, A Least Studied Aspect of the ABO System

UGC

Dr. Harsurinder Kaur

3 lac

1996

Ecobiology and Health of High Altitude Spitians

ICMR

Dr. L.S. Sidhu,         

Dr. S.P. Singh,       

Dr. Promila Mehta

3 lac

1996

Assessment of Quantitative Levels of Selected Biochemical Parameters in Normal and Abnormal Abortuses from CVS

UGC

Dr. Praveen Singhal

4 lac


Minor Research Projects

Year

     Project title

Investigator

1978

A Study of Some Malformations - Ecological Aspect

Dr. D.P. Bhatnagar

1982

Sterility in Relation to Blood Groups Incompatibility

Dr. Praveen Singhal

1983

Work Capacity, Subcutaneous Fat and Adaptive Responses

Dr. S.P. Singh

1984

Congenital Disorders in Infants and Children

Dr. D.P. Bhatnagar

1984

Rural Urban Differences in Physique and Body Composition of Adult Females of Two Endogamous Groups of Punjab

Dr. Pushpa Singal

1987

Further Studies on Dd Antigen Antibody System

Dr. Harsurinder Kaur

1988

A Biochemical Study of Diagnostic and Prognostic Significance in Breast Cancer

Dr. Promila Mehta

1989

Somatotypic Profiles of Punjabi Boys

Dr. S.P. Singh

1990

Structural Studies on the Variants of Human Serum Albumin

Dr. Harsurinder Kaur

1991

Application of Isoelectric Focusing (IEF) to Forensic Blood Genetic Marker Analysis

Dr. S.M.S. Chahal

1991

Serum LDH and its Isoenzymes and Serum Protein Polymorphisms in Carcinoma Patients of Breast

Dr. Promila Mehta

1993

High Altitude Adaptation in Spitians

Dr. S.P. Singh

1996

Erythrocyte Enzyme Variation in Two Tribal Groups of Kumaon Himalayas

Dr. S.M.S. Chahal

1996

An Assay of SCE Frequency in Peripheral Lymphocytes of Patients with Carcinoma of Reproductive System.

Dr. Satbir Kaur

1996

Ageing and Physical Activity in Women of Punjab

Dr. Pushpa Singal

1997

Physiological Maturity of Children Belonging to Different Endogamous Groups of Punjab

Dr. D.P. Bhatnagar

1998

Haemophilia : Some Genetic Investigations

Dr. Harsurinder Kaur

2001

Occupational Stress and Health Status in Women of Punjab with Special Reference to Senescence

Dr. Pushpa Singal

LIST OF ONGOING RESEARCH PROJECTS

 Year

Project Title

Investigator

Funding Agency

Amount

2013

Anthropogenetic profile of denotified tribes vimukt jatis of Punjab northwest India and its social implication

Dr. S.M.S. Chahal

UGC

13,28,300/-

2011

Genetics Polymorphism of Selected  Candidate Genes Among Alcoholic Jat Sikhs of Punjab

Dr. Rupinder Kaur

UGC

10,30.800/-

2012

" Association and gene Polymorphism of human cytokines TNF-α, IFN-ɤ ,IL-17,IL-20 and IL-22 with severity of psoriasis"

Dr. Rajinder Kaur

ICMR

30,45,000/-

2012

To find out the effect of intensive lifestyle modifications on patients with Type 2 Diabetes mellitus-a follow up study

Dr Ginjinder Kaur

UGC

10,75,000/-

Anthropometric and Biochemical assessment of adults with Down Syndrome

UGC

6,00,000/-

2013

Investigation of eNOS and ACE genes in essential hypertension for the risk of osteoporosis

Dr. Puneetpal Singh

UGC

6,00,000/- 

Genetic testing of some selected neurotransmitter genes for the risk of depression in type-2 diabetic subjects of Northwest India

UGC

13,05,300/-

 

INFRASTRUCTURE FACILITIES

The department has two centralized laboratories for doing research work in the fields of Molecular genetics, Cytogenetics and Biochemical genetics and a Computer lab with internet facility for M.Sc. and Ph.D students.


Significant Achievements

Research Achievements

Right from its beginning, the Department of Human Genetics has been actively engaged in a variety of surveys for various genetic (serological and biochemical, among others) markers on people of north west region of India, especially, those of the states of Punjab, Haryana, Himachal Pradesh, Jammu & Kashmir and Uttaranchal. A large body of data have been provided on different blood group systems (A1A2BO, Rh, MN, Kell, ABH secretion), serum protein polymorphisms (haptoglobin, albumins, transferrins, immunoglobulins) and red cell enzyme polymorphisms (ADA, AK, PGM, ESD, GLO, ACP, GPI) in addition to studies on haemoglobin variants in different caste and tribal populations inhabiting the region. Extensive data on traditional anthropogenetic parameters including PTC tasting ability, colour blindness, dermatoglyphic traits and morpho-genetic parameters have also been collected routinely. The valuable baseline data thus collected by this Department have revealed that vast reservoir of genetic heterogeneity existed in people of north west India, especially between its tribal and non-tribal components.

          Besides studying the normal genetic variation, the association of ;such genetic markers with various diseases as well as cytogenetic studies on infertility, reproductive failure, primary ammenorhea, malignancies, epilepsy and leprosy have also been taken up.

          In addition to genetic studies the Department is also engaged in exhaustive growth and physiological investigations. A synthesis of the findings of the work done so far reveals its contribution in enriching the fields of human serological, biochemical and population genetics, child growth and development, ethnic variation, senescence and physical fitness, in the Indian settings.

          The studies conducted by the Department during the last over three decades have revealed the following salient features in the people of north west India in general and Punjab in particular.

  • Genetic constitutions of the different populations inhabiting north-west India including various major caste populations like the Jat Sikh, Khatri, Brahmin, Arora and Bania of Punjab and Haryana, as well as the Brahmin and Rajput of  the hill states of Uttaranchal and Himachal Pradesh have been established thoroughly using various serological and biochemical genetic markers. In addition, various underprivileged sections of the society including the Scheduled Castes of Punjab, Haryana and Uttaranchal as well as the Scheduled Tribes of Uttaranchal and Himachal Pradesh have also been characterized genetically. Similar genetic studies have also been conducted on the minority community of the Muslims of Punjab state.
  •  Besides normal variation studies, the Department has carried out surveys for the detection of various abnormal blood genetic traits namely haemoglobinopathies, haemophilia, cis-AB and rare variants of serum proteins and red cell enzymes.
  • The role of genetical markers in reproductive failure and malignancies has been studied extensively. The markers studied include blood groups, secretor status, haptoglobins as well as chromosomal preparations from the blood.
  • The role of various genetical markers in forensics has also been investigated. Studies have been made to type latent fingerprints, nails, hair roots, CVS and blood stains for blood groups and blood stains as well as hair roots for red cell enzyme polymorphisms.
  • Determination of zygosity of twins has also been attempted on the basis of various genetical traits including blood groups, dermatoglyphics and morphogenetical characteristics.
  • Pedigree studies have been undertaken for investigations of inheritance of rare variants and genetical disorders detected in different surveys.
  • Results of blood group typings have been sent to thousands of subjects of the various field work surveys conducted especially in the neighbouring hill states of Himachal Pradesh and Uttaranchal, among others.
  • The Department has provided serological, biochemical and cytogenetic analytical facilities to the patients referred to by various medical hospitals/ institutions of this region.
  • Research on growth performance of children belonging to different socio-economic strata has indicated a retarded growth of lower strata children.
  • Ethnic differences have been noticed in the growing children and adults in Punjab where the dominant caste (the Jat Sikh) outclasses all other caste groups.
  • The urban areas of Punjab register better growth of children than the rural areas.
  • Research on life style of rural females revealed that they possess better health than their urban counterparts. The former are also taller and leaner than the latter.
  • Researches on ageing pattern in working and non-working females have suggested beneficial effect on mental and physical outlooks in working women.
  • The standard measurement chart for garments of children from 3 to 5 years has been prepared.
  • Growth standards for the Punjabi population have been established.
  • The female child in the underprivileged setting of Punjab is slow in cognitive abilities than the male child.
  • Menarcheal and menopausal ages are also influenced by the socio-economic stratification, climate, season of the year, urbanization, type of diet and caste stratification.
  • The state of Punjab has been witnessing trends of earlier maturation of its children over the past few decades. The present generation of children are becoming larger and taller as well (secular growth shifts).
  • The skeletal maturity of children in Punjab highlights the advanced maturity of those participating in sports than the control group.
  • The high altitude children of Spiti, Chamba and Leh in north west India do not grow favourably obviously because of the altitudinal stresses including hypoxia.
  • Projects relating to AIDS awareness and hepatitis B have been taken up in this region.

          The above findings have been highlighted by the Faculty and researchers of the department at both national and international fora from time to time.

COLLABORATIONS

Faculty members of the Department have been collaborating for their joint research projects / activities with other research/ teaching departments of the Punjabi University  as well as with other Universities/ Hospitals/ Research Institutions.
(a)      National Collaboration

  • National Institute of Sports, Patiala.
  • Govt. Rajindra Medical College/Hospital, Patiala.
  • Christian Medical College, Ludhiana.
  • Department of Anthropology, University of Delhi, Delhi.
  • Maulana Azad Medical College, Delhi.
  • National Institute of Family Planning and Welfare, Delhi.
  • Department of Zoology, Kurukshetra University, Kurukshetra, Haryana.
  • State Forensic Science Laboratory, Madhuban, Haryana.
  • Central Avian Research Institute, Izzatnagar, Bareilley, Uttar Pradesh.
  • Anthropological Survey of India, Dehradun, Uttar Pradesh.
  • Punjab Institute of Development Studies (N.G.O.).
  • Advanced Instrumentation Research Facility Jawaharlal Nehru University, New Delhi.

(b)      International Collaboration

  • Department of Human Biology and Anthropology, University of Bremen, Bremen, Germany
  • Department of Human Genetics, University of Newcastle upon Tyne, Newcastle upon Tyne, England
  • Department of Anthropology, Southern Illinois University, U.S.A.
  • Department of Radiology (Section of Cancer Biology), New Jersey Medical School, New Jersey, U.S.A.
  • Department of Physical Anthropology, Eotvos Lorand University, Budapest, Hungary

 

                                                                                                                                                         Contact Us

                                                                                                                                               Name:
Satbir Kaur
                                                                                                                                             Department of Human Genetics
                                                                                                                                          Punjabi University, Patiala,Punjab.
                                                                                                                                             Pin -147002
  Ph: 0175-304-6277

 


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