The fourth teporal seat (Takhat) of Sikh religion is situated at this sacred land of Talwandi Sabo. Battling with his contemporary tyrant rulers, Guru Gobing Singh ji left Sri Anandpur Sahib in 1704 and traveling through the places of Chamkaur Sahib, Maachhiwara, Deenagarh, Mukatsar Sahib, Lakhhi Jangal, Pakka Pathrala etc., reached here in 1705. The revered Guru stayed here for more than fifteen months and this place became popular as "Damdama Sahib". Here, Guru Ji got written the sacred bir of Aad Sri Guru Granth Sahib by the great martyr Bhai Mani Singh ji and blessed this land as "Guru Ki Kashi". Shaheed Baba Deep Singh ji was the first Jathedar (head) of this temporal seat. He prepared the copies of Aad Sri Sahib and sent to other four temporal seats of Sikh religion. The auspicious occasion of Vaisakhi is being celebrated at this place with great enthusiasm and devotion.
Guru Kashi Campus of the Punjabi University was set up in 1988 for transforming the education scene in the heart of the Malwa region of Punjab. The unique distinction of the Guru Kashi Campus is that it is highly oriented towards the extension of professional education in the management and computer application areas in an otherwise backward rural region. At this Campus, the University School of Business Studies has been created to fill a vital gap in management education. The establishment of Yadavindra College of Engineering at this Campus is proving a catalyst for the overall development of this region. The YCoE institute is totally based on the new and unique idea where the students from rural areas are being provided free education through the scholarships. Punjabi University Guru Kashi College, Talwandi Sabo(PB) , which was started in the 1960s has become an integral part of the Campus. B.A. & B.Sc. courses are being offered in this institute.